What is the histologic hallmark of invasive ductal carcinoma of the breast?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the Histopathology and MTLE Test. Prepare with flashcards and multiple choice questions. Gain insights into the exam format, essential topics, and tips to excel your preparation!

Multiple Choice

What is the histologic hallmark of invasive ductal carcinoma of the breast?

Explanation:
The key histologic feature is malignant ductal epithelial cells that breach the basement membrane and invade the surrounding breast stroma, typically provoking a desmoplastic (dense fibrous) stromal reaction. This invasion distinguishes invasive ductal carcinoma from noninvasive forms, where malignant cells are confined within ducts and the basement membrane remains intact with no stromal invasion. The desmoplastic stroma plus invasive growth pattern—often seen as irregular cords, nests, or tubules of malignant cells within fibrous tissue—defines this carcinoma.

The key histologic feature is malignant ductal epithelial cells that breach the basement membrane and invade the surrounding breast stroma, typically provoking a desmoplastic (dense fibrous) stromal reaction. This invasion distinguishes invasive ductal carcinoma from noninvasive forms, where malignant cells are confined within ducts and the basement membrane remains intact with no stromal invasion. The desmoplastic stroma plus invasive growth pattern—often seen as irregular cords, nests, or tubules of malignant cells within fibrous tissue—defines this carcinoma.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy